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Are present in the predictions, PF-SVM significantly outperforms PSI-Blast by ranking more true positives at the top of the rank list. At a given threshold of 10 false positives, the PF-SVM detects 4 more proteases than PSI-Blast in the P. falciparum genome (12 vs 8), 1 more in the P. vivax genome (19 vs 18) and 6 more in the P. yoelii yoelii genome (9 vs 3). Overall, PF-SVM performs better on the