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Major capsid protein L1 produced in S. cerevisiae. In 2009 the FDAMajor capsid protein L1 produced in S. cerevisiae. In 2009 the FDA approved Cervarix, a bivalent (HPV types 16 and 18) vaccine commercialized by GlaxoSmithKline (GSK). Both the HPV VLP vaccines have shown to have a sustained prophylactic efficacy in clinical trials against infection and genital disease, generating a long-lasti