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Ray facility. JH, RM, JP, EB and JV contributed to the design of the experiments and interpretation of the data. EW conceived, designed and coordinated experiments, helped interpreting the data and drafting the manuscript. All authors have read and approved the manuscript. Acknowledgements The authors are grateful to Dr. Seiji Nato (Kyushu University, Fukuoka, Japan) and to Dr. Kevin Scanlon (Keck