Superfamily members include insect venom allergens, plant pathogenesis family-1 (PR-1) proteins and VAL proteins beside mammalian cysteine-rich sperm proteins (CRISPs). No rational function for this protein family has been demonstrated despite the sequence similarity [8]. Astacinlike metalloproteases are vital for establishment of the parasite in the host. MTP-1 and the astacin-like MTP secreted b