SMT Discover - Fildena 50mg Some medicines are not safe to take with Fildena 25 mg. Specifically, Fildena 50 mg shouldn’t be used in combination with a nitrate drug for treating chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, amyl nitrate, or nitrite "poppers." Tue, 31 Jul 2018 12:27:54 UTC en