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Alarmolive6

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To protein Variable degree of carrier immunogenicity; need adjuvants (and oftenTo protein Variable degree of carrier immunogenicity; need adjuvants (and often multiple doses); frequent local reactions at the injection siteHumoral immunityDiphtheria; tetanus; pertussis; haemophilus influenzae type b; poliomyelitis; rabies; meningitidis; Japanese encephalitis; cholera; hepatitis A; hepatitis B
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Efficiency; enhanced permeability; biodegradability and biocompatibilityHepatitis B and Haemophilus influenzae typeEfficiency; enhanced permeability; biodegradability and biocompatibilityHepatitis B and Haemophilus influenzae type b; influenza; meningococcus, pneumococcus, and Haemophilus influenzae type B polysaccharides Infectious haematopoietic necrosis virus; West Nile virus; melanoma; g
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Require further optimization. In addition to viral vectors, recombinant bacterial carriersRequire further optimization. In addition to viral vectors, recombinant bacterial carriers, derived from lactic acid bacteria, Salmonella and L. monocytogenes strains, have been used extensively as delivery systems being able to stimulate both systemic [29,30] and mucosal immune responses .GENE DELIVERY
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Require further optimization. In addition to viral vectors, recombinant bacterial carriersRequire further optimization. In addition to viral vectors, recombinant bacterial carriers, derived from lactic acid bacteria, Salmonella and L. monocytogenes strains, have been used extensively as delivery systems being able to stimulate both systemic [29,30] and mucosal immune responses .GENE DELIVERY
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To protein Variable degree of carrier immunogenicity; need adjuvants (and oftenTo protein Variable degree of carrier immunogenicity; need adjuvants (and often multiple doses); frequent local reactions at the injection siteHumoral immunityDiphtheria; tetanus; pertussis; haemophilus influenzae type b; poliomyelitis; rabies; meningitidis; Japanese encephalitis; cholera; hepatitis A; hepatitis B
1
To protein Variable degree of carrier immunogenicity; need adjuvants (and oftenTo protein Variable degree of carrier immunogenicity; need adjuvants (and often multiple doses); frequent local reactions at the injection siteHumoral immunityDiphtheria; tetanus; pertussis; haemophilus influenzae type b; poliomyelitis; rabies; meningitidis; Japanese encephalitis; cholera; hepatitis A; hepatitis B
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Ds virulent forms and can be local reactions at the usedDs virulent forms and can be local reactions at the used in immunodeficient hosts; not vaccine site) are required heat-labile to optimally trigger the adaptive immune system and generate long-term immunity; do not give rise to cytotoxic T cells; poor induction of mucosal immunity; difficult to produce in a scalable setting; quality and
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Ne responses; highly immunogenicity in human stable; easy storage and transportNe responses; highly immunogenicity in human stable; easy storage and transport; compared to mice; low large-scale production; optimization transfection efficiency of plasmids and transcript is possibleActivation of antigen-specific B cells, CD4+ and CD8+ T cellsVectored vaccinesNanoparticlesLive recombinant Abili