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N defense or digestion [67]. WD40 repeats (also known as WD or betatransducin repeats) are involved in signal transduction and transcription regulation along with cell-cycle control and apoptosis [68,69]. Heat shock proteins, such as HSP-20 are reported to be present in the parasitic nematode, H. contortusMenon et al. BMC Genomics 2012, 13(Suppl 7):S10 http://www.biomedcentral.com/1471-2164/13/S7/
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N defense or digestion [67]. WD40 repeats (also known as WD or betatransducin repeats) are involved in signal transduction and transcription regulation along with cell-cycle control and apoptosis [68,69]. Heat shock proteins, such as HSP-20 are reported to be present in the parasitic nematode, H. contortusMenon et al. BMC Genomics 2012, 13(Suppl 7):S10 http://www.biomedcentral.com/1471-2164/13/S7/
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Cades. Nematode enzymes mapped to known human disease pathways such as Huntington's disease, Alzheimers disease, Parkinson's disease and Vibrio cholerae infection. The neurological disorder pathways are known to describe the morbidity and depression associated with helminthic infections. The Vibrio cholera infection pathway supports this parasite being similar to gastrointestinal strongylid nemato
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Cades. Nematode enzymes mapped to known human disease pathways such as Huntington's disease, Alzheimers disease, Parkinson's disease and Vibrio cholerae infection. The neurological disorder pathways are known to describe the morbidity and depression associated with helminthic infections. The Vibrio cholera infection pathway supports this parasite being similar to gastrointestinal strongylid nemato
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Ating protein (SCP)-like extracellular proteins, also called SCP/Tpx-1/Ag5/PR-1/Sc7, play major biological roles in the host-pathogen interplay [60] along with other groups of proteins [61] . NADP+ plays a vital role in developmental process and also acts as a reducing agent in anabolism along with NAD + , a coenzyme involved in key pathways like glucose metabolism and fatty acid synthesis [62]. I
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Ating protein (SCP)-like extracellular proteins, also called SCP/Tpx-1/Ag5/PR-1/Sc7, play major biological roles in the host-pathogen interplay [60] along with other groups of proteins [61] . NADP+ plays a vital role in developmental process and also acts as a reducing agent in anabolism along with NAD + , a coenzyme involved in key pathways like glucose metabolism and fatty acid synthesis [62]. I
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On BLASTP against the NR database (Additional File 13). Different classes of proteases are assigned based on the catalytic mechanisms and are named based on their active catalytic centre residues (aspartic, serine and cysteine proteases) or after their dependence on co-factors for activity (metalloproteases). Of the four classes of proteases aspartic proteases are considered to be the most conserv
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On BLASTP against the NR database (Additional File 13). Different classes of proteases are assigned based on the catalytic mechanisms and are named based on their active catalytic centre residues (aspartic, serine and cysteine proteases) or after their dependence on co-factors for activity (metalloproteases). Of the four classes of proteases aspartic proteases are considered to be the most conserv